Piers Morgan, the guy barely anyone knows in the U.S. who took over for Larry King, has confirmed the guest list for his first full week on the air.

Oprah Winfrey will kick off “Piers Morgan Tonight” on January 17th — calling the recently taped segment “one of the toughest interviews I’ve had in 20 years.” Guest later in the week include Howard Stern, Condoleezza Rice, Ricky Gervais, and George Clooney and his father Nick Clooney.

Inviting both Clooneys on the program is indicative that the focus of the interview will almost certainly be on the situation in the Sudan. Both father and son have traveled to the region repeatedly to document and raise attention of the humanitarian crisis still unfolding. Late last year, George Clooney announced the Satellite Sentinel Project in partnership with Google, the U.N. and other Darfur relief organizations. The purpose of the high-tech initiative is to monitor the situation in Southern Sudan — currently voting on whether or not to gain independence. “We are the anti-genocide paparazzi,” Clooney told Time. “We want them to enjoy the level of celebrity attention that I usually get. If you know your actions are going to be covered, you tend to behave much differently than when you operate in a vacuum.”

The 49-year-old most recently arrived in Juba on Thursday in a show of support for the region still recovering from decades of war. As for people who criticize him for attempting to make a difference, Clooney told the AFP, “If they don’t like what we are trying to do, then get out of the way, I don’t care.”

“We try to save some people’s lives,” he added. “If we succeed then good, if we did not we tried. I don’t see a downside to that.”

George and Nick Clooney with Piers Morgan will air on January 21st on CNN at 9PM/EST.

About Michael dEstries

Michael has been blogging since 2005 on issues such as sustainability, renewable energy, philanthropy, and healthy living. He regularly contributes to a slew of publications, as well as consulting with companies looking to make an impact using the web and social media. He lives in Ithaca, NY with his family on an apple farm.

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